منابع مشابه
Myosins pull together—separately
D on’t tell your high school football coach, but it is possible to have teamwork even if nobody’s in charge. Inside a cell, for example, myosin VI motors work in concert to haul cargoes along the actin cytoskeleton, Sivaramakrishnan and Spudich reveal (1). Instead of providing muscle power, myosin VI is one of the unconventional myosins whose job is intracellular transportation. Researchers hav...
متن کاملPurchasing prescription drugs in Canada: hang together or hang separately.
Canada's provincial and territorial governments have expressed an interest in bulk purchasing prescription drugs for many years. We propose they start by purchasing selected generic drugs for the entire population and provide them for little or no cost to patients. This politically popular strategy would significantly reduce drug expenditures and improve population health.
متن کاملPharmacokinetic and safety profile of raltegravir and ribavirin, when dosed separately and together, in healthy volunteers.
BACKGROUND Treatment of chronic hepatitis C virus (HCV) infection in HIV-1-co-infected individuals remains challenging due to numerous factors, including drug-drug interactions. The aim of this study was to assess the safety and pharmacokinetic (PK) profile of raltegravir and ribavirin when dosed separately and together. METHODS Fourteen healthy volunteers [mean (standard deviation) age 35 (1...
متن کاملInfluence of grazing cattle and sheep together and separately on animal performance and forage quality.
Cattle and sheep grazed together and separately from April to October during 3 yr. Initial forage composition was 29% Kentucky bluegrass (Poa pratensis L.), 11% white clover (Trifolium repens L.), and 60% weeds. There were six Angus cow-calf pairs or six ewes (1/2 Dorset x 1/4 Finn x 1/4 Rambouillet) with 11 lambs per each of three pasture replications for single animal species. Six cow-calf pa...
متن کاملTogether or Separately? Issues on the Costs and Benefits of Political and Fiscal Unions
This paper shows that in American states balanced budget rules are effective in enforcing fiscal discipline but they have no costs in terms of increased output variability. More specifically, we show that tighter fiscal rules are associated with larger average surplus and lower cyclical variability of the budget balance. However, the lower flexibility of the budget balance does not affect state...
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2004
ISSN: 1061-4036,1546-1718
DOI: 10.1038/ng0104-12